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Keep this study
Lead
University of California, Davis
The primary aim of this study:
1. To assess the correlation between elevated brain natriuretic peptide levels and elevated thoracic impedance/body fluid index as measured by selective biventricular resynchronization devices and an external impedance cardiography device.
2. Correlate impedance measurements and brain natriuretic levels with occurrence of atrial and ventricular arrhythmias as assessed by interrogation of biventricular devices.
Age
18–85
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Male or female between 18 to 85 years of age.
All patients with biventricular implantable cardio-defibrillators(manufacturer: Medtronic/ model: InSync 7299/7297 or newer).
LVEF \<35%
NYHA III/IV
QRS \>120 msec
Pt willing and able to sign informed consent.
Conventional heart failure therapy
Clinically stable for six months.
You may not be if
age less than 18 years of age
age greater than 85 years of age
Creatinine \> 2.5 mg/dl.
End stage liver disease complicated by ascites as determined by electronic medical record review.
women who are pregnant, lactating, or plan to become pregnant during the course of the study.
Patients who are heart transplant candidates with expected transplantation within the next six months.
Life expectancy due to non-cardiac cause less than one year.
Anticipated problem with compliance.
Critical valvular stenoses/insufficiencies.
Morbidly obese patients(\>300 lbs.)
In patients whom impedance cardiography was not able to be performed because of inability to place sensors.
Planned or known need for revascularization procedures within three months.
Clareo Health | Comparison Study of BNP and Thoracic Impedance Measurements on Arrhythmias
