Allogeneic Stem Cell Transplantation for Patients With Severe Aplastic Anemia

Exclusion Criteria

• •Patients with Aplastic anemia and active infection must be treated to maximally resolve this problem before beginning the conditioning regimen.
• •HIV seropositive patients
• •Patients who have clonal cytogenetic abnormalities or a myelodysplastic syndrome.
• •Patient greater than 60 years of age.
• •Women who are pregnant or nursing.
• •Patients with active hepatitis
• •Patients with severe cardiac dysfunction defined as shortening fraction \<25%.
• •Patients with severe renal dysfunction defined as creatinine clearance \<40ml/mim/1.73m2.
• •Patient with severe pulmonary dysfunction with FEV1, FVC and DLCO 40% of predicted or 3 SD below normal.