Duke Conte Center for the Neuroscience of Depression in Late Life

Exclusion Criteria

• •1. Lifetime alcohol or drug dependence
• •2. Conditions associated with MRI abnormalities such hydrocephalus, benign and cancerous brain tumors, epilepsy, Parkinson's disease, Huntington's chorea, dementia, demyelinating diseases, etc.
• •3. Endocrine disorder (other than diabetes mellitus)
• •4. Any physical or intellectual disability that may affect completion of self rating instruments
• •5. Established clinical diagnosis of dementia
• •6. Other primary psychiatric disorders, including panic disorder, social phobia, OCD, non-affective psychosis (including schizo-affective disorder), schizophrenia, bipolar disorder
• •7. Any metal or pacemaker in the body which precludes MRI.