Male patients with an initial presentation of organ confined prostate cancer;(clinical stages T1c and T2a only)
Age 40 yrs. and older up to and including age 80 yrs.
Anesthesia Surgical Assignment (ASA) categories I, II or III only
PSA levels equal tyo or less than 10ng/ml
Pre-HIFU Gleason score equal to or less than 7
Clearly imageable prostate on TRUS
Prostate total volume less than 40cc with an AP height less than or equal to 4.2cm. (If volume is greater than 40cc or height greater than 4.2 cm, one 3 monthly shot of an LHRH analogue may be provided, followed by re-imaging of the prostate to document total volume below 40cc.)
You may not be if
Large calcification in the area to be treated (\>5mm)
Bleeding disorder as determined by abnormal prothrombin time (INR) and partial thromboplastin time (PTT)
Pt. on Coumadin or any other anticoagulent, unless their anticoagulation an be temporarily reversed or stopped
Urinary tract infection unless treated satisfactorily by antibiotics and documented by a sterile urine culture
Interest in future fertility
History of allergy to latex
Inability to visualize the prostate tissue adequately on transrectal ultrasound imaging
History of treatment for prostate cancer (except for one LHRH analogue "shrinkage shot")
History of TURP, thermotherapy or urethral stent
History of any major rectal surgery
History of inflammatory bowel disease
History of urinary bladder neck contracture
History of any other malignancy other than skin cancer. Patients that have had a previous malignancy and no recurrence of that malignancy within the past 5 years will be allowed; (superficial bladder cancer is OK of clear for 2 years)
Inability to be placed in lithotomy position Prior long term hormonal therapy for prostate cancer (including bilateral orchiectomy).
Clareo Health | Treatment of Localized Prostate Cancer With High Intensity Focused Ultrasound Using the Sonablate® 500 System in Canada
