Treatment of Polytraumatisms With Corticoids

Interest of Treatment of Polytraumatisms With Corticoids (Hydrocortisone) for Patient With Relative Adrenocortical Insufficiency

NCT00563303•Nantes University Hospital

View on ClinicalTrials.gov

Summary

Interest of treatment of polytraumatisms with corticoids (hydrocortisone) for patient with relative adrenocortical insufficiency on frequency of nosocomial infection, and hemodynamic complications and organs injuries.

Eligibility

Age

15 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Age superior of 15 years
•Hospitalization in reanimation for polytraumatism (lesion of two organs with a vital risk)
•SISS score more than 15
•Intubation for more than 48 hours.
•Agreement of a family member
•Patient with insurance

Exclusion Criteria

•History of corticothérapies within 6 months
•History of adrenocortical insufficiency.
•Treatment by immunosuppressor
•Immunodeficiency.

Locations (7)

CHU Bordeaux

Bordeaux, France

CHU Morvan de Brest

Brest, France

CHU Caen

Caen, France

CH La Roche Sur Yon

La Roche-sur-Yon, France

Hôtel Dieu

Nantes, France

CHU Pontchaillou

Rennes, France

CHU Trousseau

Tours, France

Key Dates

Start Date

November 1, 2006

Primary Completion Date

November 1, 2006

Completion Date

July 1, 2009

Last Updated

April 23, 2010

Enrollment

150

ACTUAL participants

Conditions

Polytraumatism

Interventions

hydrocortisone

DRUG

NaCl

DRUG