Topical Avastin for Treatment of Corneal Neovascularization

Exclusion Criteria

• •Current or recent (≤ 1 month) systemic corticosteroid therapy or periocular corticosteroid injections to the study eye
• •Current or recent (≤ 3 months) intravitreal drug injection to the study eye; recent (≤ 1 month) change in dose and frequency of topical steroids and/or non-steroidal anti-inflammatory agents
• •Uncontrolled hypertension defined as systolic blood pressure of ≥ 150 mmHg or diastolic blood pressure of ≥ 90 mmHg; history of a thromboembolic event, including myocardial infarction or cerebral vascular accident
• •Patients age 75 or older; history of renal abnormalities
• •Recent (≤ 3 months ) or planned surgery
• •History of coagulation abnormalities, including end stage liver disease or current anticoagulation medication other than aspirin (warfarin, heparin, enoxaparin, or similar anticoagulant agent)
• •All female patients of childbearing potential (a female is considered to be of childbearing potential unless she is postmenopausal and without menses for 12 months or without a uterus and/or both ovaries)
• •Any condition (including language barrier) that precludes patient's ability to comply with study requirements including completion of study