Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Texas Southwestern Medical Center
Secondary objectives:
1. Demonstrate that patient acceptance is greater and diuresis faster with a No Added Salt diet compared with a Low Sodium diet
2. Demonstrate that side-effects of diuretic therapy are the same or less when patients are on a No Added Salt diet
3. Determine if glomerular filtration rate estimated from the modified diet in renal disease equation differs from that obtained by a 24 hour urinary creatinine in patients with cirrhotic ascites
Age
18–75
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Cirrhotic patients of any etiology with ascites from portal hypertension diagnosed by paracentesis,
Age 18-75
Clinical or radiographic (abdominal CT or ultrasound) estimate of moderate - severe ascites
Spanish-speaking subjects will be eligible for participation
You may not be if
Active drug or alcohol abuse,
Active complications of SBP, hepatic encephalopathy, or GI bleed within 2 weeks,
Hemorrhagic ascites, malignant ascites,
Creatinine \>2 mg/dL or CCl \< 30 mL/min,
K \> 5.5 mmol/L,
Diuretic refractory ascites
Allergy to or intolerance of either spironolactone or furosemide
Homelessness, incarceration, inability to follow up in clinic, or comply with diet.
Clareo Health | Sodium Restriction in the Management of Cirrhotic Ascites
