Prevention of Recurrence of Diverticulitis

Exclusion Criteria

• •1. Previous colorectal surgery, including surgical intervention for diverticular disease (with the exception of haemorrhoidectomy, colonic removal of polyps, and appendectomy)
• •2. Active peptic ulcer disease
• •3. History of or current presence of inflammatory bowel disease (IBD)
• •4. Subjects with active irritable bowel syndrome (IBS) requiring ongoing medication
• •5. Allergy or hypersensitivity to aspirin or related compounds
• •6. Allergy to radiologic contrast agents
• •7. Use of another Investigational product within 30 days of Baseline
• •8. Use of antibiotic therapy within 4 weeks of Baseline
• •9. Within 14 days of Baseline, use of prebiotic, probiotic or 5-ASA medications, as well as drugs active at the 5HT-receptor or anti-spasmodic agents
• •10. Use of systemic or rectal steroids within 6 weeks of Baseline. Use of inhaled or nasal steroids is acceptable
• •11. Use of anti-inflammatory drugs, (NSIADs, COX-2 inhibitors) including aspirin (except for cardiac prophylaxis) and ibuprofen, on a regular and ongoing basis
• •12. History of alcohol or other substance abuse within the previous year
• •13. Active or recent history of endometriosis or dysmenorrhoea within 6 months prior to Baseline
• •14. Females who are lactating