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Cytokine Removal by CRRT in Pediatric Sepsis | Clinical Trials | Clareo Health

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COMPLETEDNANCT00537693

Cytokine Removal by CRRT in Pediatric Sepsis

This pilot study will compare the effect of diffusive versus convective Continuous Renal Replacement Therapy (CRRT) in children with sepsis who require CRRT. The hypothesis for the study is that conv...

Lead sponsor: Sunnybrook Health Sciences Centre•5 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Sunnybrook Health Sciences Centre

Collaborators

Dialysis Solutions Inc.

The purpose of this study is to test the hypothesis that convective forms of Continuous Renal Replacement Therapy (CRRT) provides enhanced clearance of cytokines compared to a diffusive CRRT modality. Also, we plan to test the hypothesis that patients who receive convective CRRT modalities demonstrate improved clinical responses to patients who receive a diffusive CRRT modality.

Age

1 - 21 years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Patients with documented sepsis or suspected SIRS
•Patients initiating CRRT
•Age 1 to 21 years

Exclusion Criteria

•Patients on ECMO
•Patients receiving concomitant plasma exchange
•Cardiopulmonary bypass procedure within 96 hours of CRRT
•Patients with new onset acute leukemia
•Patients with active autoimmune disease
•Ungrafted stem cell transplant recipients

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: September 2, 2010Terms

Trial snapshot

StatusCOMPLETED

PhaseNA

Enrollment40

Start dateSep 2007

Last updatedSep 2, 2010

Condition

Locations shown

Children's National Medical Center

Washington D.C., District of Columbia

All Children's Hospital

St. Petersburg, Florida

Children's Healthcare of Atlanta

Atlanta, Georgia

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: September 2, 2010Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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