Effect of SBG in Patients With Breast Cancer

Exclusion Criteria

• •1. Women who are pregnant or breast-feeding. A negative pregnancy test must be provided during the screening period for fertile women. Fertile women must use effective contraceptive methods
• •2. Clinical symptoms indicating central nervous system involvement
• •3. Other current or former malignant disease, with the exception of adequately treated and cured carcinoma in situ cervicis uteri and basocellular skin carcinomas
• •4. Left ventricular ejection fraction (LVEF) \< 50% of normal range
• •5. Reduced bone marrow function defined by leukocyte counts \< 3.0 x 109/l and neutrophil counts \< 1.5 x 109/l, or thrombocyte counts ≤ 100 x 109/l
• •6. Reduced liver function defined by bilirubin \> 3 x upper normal limit and/or ASAT/ALAT \> 3 x upper normal limit and/or alkaline phosphatase \> 3 x upper normal limit.
• •7. Reduced renal function defined by serum creatinine \> 2 x upper normal limit