Trial Comparing Tiotropium Inhalation Capsules vs Placebo in Chronic Obstructive Pulmonary Disease (COPD).

Exclusion Criteria

• •Subjects who have been treated with maintenance medications for chronic respiratory disease within six months prior to screening.
• •Subjects with significant diseases other than COPD. Subjects on chronic systemic corticosteroids.
• •Subjects with any upper and/or lower respiratory tract infection or COPD exacerbation in the 6 weeks prior to the initial visit 1 or during the screening period prior to visit 3 Subjects with a recent (past 6 months) myocardial infarction, any unstable or life threatening cardiac arrhythmia requiring intervention or change in drug therapy during the last year; or who have been hospitalized for cardiac failure during the past year.