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COMPLETEDPhase 2NCT00520910

Efficacy of Polypodium Leucotomos Extract Decreasing UVA Premutagenic and Photoaging Markers

With this study, the investigators will like to determine if taking a dose of the study medication, called Polypodium leucotomos (PL), prevents some of the changes in the skin caused by the adverse ef...

Lead sponsor: University of Miami•1 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

University of Miami

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Healthy subjects,
•18 years of age or older,
•with Fitzpatrick skin types II and III.

Exclusion Criteria

•Pregnancy
•Personal history of skin cancer
•History of abnormal photosensitivity
•Smokers
•Patients with history or being exposed to other forms of radiation (other than sunlight)
•History or current exposure to asbestos
•Patients taking any drug that might alter the response of skin to UVR (including, but are not limited to, doxycycline, sulfas, psoralens, and amiodarone)
•Patients unable to undergo skin biopsies
•History of abnormal scarring
•History of adverse reaction to local anesthesia

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: June 18, 2019Terms

Trial snapshot

StatusCOMPLETED

PhasePHASE2

Enrollment10

Start dateAug 2007

Last updatedJun 18, 2019

Condition

Aging Skin Abnormalities

Locations shown

University of Miami Skin Research Group Office

Miami, Florida

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: June 18, 2019Data synced to Clareo: April 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions