Trial of Quetiapine in Anorexia Nervosa

Exclusion Criteria

• •Subjects will not be included in the study who present with any of the following:
• •Schizophrenia or schizoaffective disorder (DSM-IV)
• •Any ECG abnormality considered clinically significant by the investigator
• •Subjects with liver enzymes elevated two times or more above normal
• •Other laboratory abnormalities considered clinically significant by the investigator including laboratory deviations requiring acute medical intervention
• •Pregnant women, women of childbearing potential not using medically accepted means of contraception (abstinence, IUD, birth control pills, barrier devices or implanted progesterone rods stabilized for at least three months), and lactating women
• •Serious suicide risk
• •Any medical condition that would preclude the outpatient treatment of anorexia nervosa or the use of quetiapine
• •Organic brain disease
• •History of severe allergies
• •Multiple adverse drug reactions or known allergy to quetiapine
• •Use of neuroleptic medications (except benzodiazepines) within 7 days preceding randomization
• •History of alcohol or substance abuse disorder as defined in the DSM-IV within the past 3 months.