Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of California, San Francisco
Age
15–61
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
No fully or single-antigen mismatched sibling donor is available to donate stem cells.
Age \>15 and \<61
ECOG PS \< or equal to 2
Adequate renal function with serum creatinine \<2.0 mg/dl
Pulmonary diffusing capacity \>40% of predicted
Cardiac ejection fraction \>40% as measured by radionuclide wall motion study or echocardiography
No active liver disease. Total bilirubin must be \< or equal to 2.0 mg/dl. Alkaline phosphatase and AST must be less than three times the upper limit of normal. Patients with hepatitis C and active hepatitis B are eligible only if a liver biopsy is performed and there is \< or equal to grade 2 inflammation. Patients wtih a history of HBV infection should be tested for HBeAg, antiHBe and HBV DNA (quantitative). Patients with active HBV viral replication should receive anti-viral therapy.
Negative serology for the human immunodeficiency virus (HIV)
Available HLA-matched donor (see HLA compatibility requirements below)
Signed informed consent from the recipient
You may not be if
Ongoing active infection
Pregnancy and/or nursing
Active, uncontrolled CNS leukemia
Opinion of BMT Committee that autologous or mini-allogeneic transplant would be the preferable form of treatment
Receipt of any chemotherapy within 3 weeks of study entry except for hydroxyurea or imatinib mesylate. Use of interferon within 3 months of starting therapy.
