A Study to Evaluate and Study Drug Levels in Blood Plasma When Giving High Doses of GSK189075 to Healthy Volunteers

Exclusion Criteria

• •history of drug or alcohol abuse within one year of the study screening.
• •use of tobacco or nicotine-containing products with 6 months prior to the study screening.
• •use of any prescription or non-prescription drugs, vitamins, herbal, and dietary supplements within 14 days of the start of the study.
• •blood donation within 56 days before the start of the study
• •receiving other investigational drugs or participating in other research trials within 30 days of the start of this study.