Efficacy of ThermoProfen in Patients With Mild to Moderate Pain Associated With Osteoarthritis of the Knee

Exclusion Criteria

• •Patient has a known allergy to nonsteroidal anti-inflammatory drugs (NSAIDs, including aspirin).
• •Patient has asthma that has been induced or made worse by the use of aspirin or NSAIDs.
• •Patient has a relevant history of serious gastrointestinal disease.
• •Patient, if female, is pregnant or breastfeeding or is of childbearing potential and not practicing adequate birth control.
• •Patient is taking warfarin, heparin, or low molecular weight heparin.
• •Patient has received oral, intramuscular, intravenous, intra-articular, or soft-tissue administration of steroids within 1 month of study enrollment (or within 2 months, if in the target joint).
• •Patient has received intra-articular visco-supplementation (in target joint) within 6 months of study enrollment.