Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Chromaderm, Inc.
With
Joslin Diabetes Center
32mg Ruboxistaurin; 4 week cross-over treatment.
Age
18–70
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Type 2 diabetes diagnosed for at least 1 mo and less than 10 yrs prior to visit 1
HbA1c less than 9% and fasting plasma glucose less than 260mg/dl
Blood pressure less than 160/100 mmHg
Total cholesterol less than 300 mg/dl and/or triglycerides less than 600 mg/dl
You may not be if
Subjects treated with a thiazolidinedione (TZD) in 12 weeks prior to visit 1.
History of heart disease (MI, unstable angina, CVA, TIA, CABG, or percutaneous transluminal coronary angioplasty) w/in 6 months of visit 1 or subjects with BYHA class III or IV congestive heart failure.
Female subjects of child-bearing potential that are pregnant or intend to become pregnant (i.e. not practicing an acceptable method of birth control)
TSH greater than 1.5 times upper limit of normal at V1 or other endocrine disease.
ALT greater than 1.5 times upper limit of normal at V1; Serum creatinine greater than 2.0mg/dl at V1; micro-albumin greater than 300.
