Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Genentech, Inc.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Ability to understand and willingness to sign a written informed consent
Histologically or cytologically confirmed NSCLC
Advanced NSCLC
Measurable disease
ECOG performance status of 0 or 1
Age ≥ 18 years
Use of accepted and effective method of contraception, i.e., double barrier contraceptive methods (e.g., diaphragm plus condom) or abstinence during the course of the study and for 6 months after the last study treatment administration for women, and 1 month for men
You may not be if
Squamous cell histology
Prior malignancy other than NSCLC (except in situ basal cell carcinoma or in situ cervical cancer), unless it has been treated with curative intent and there is no evidence of disease for ≥ 3 years prior to randomization
Untreated or unstable CNS metastases
Myocardial infarction or an unstable or uncontrolled disease or condition related to or impacting cardiac function within 1 year prior to randomization
Uncontrolled hypertension
History of arterial thrombosis, stroke, or serious hemorrhagic disorder within 1 year prior to randomization
Major surgical procedure within 28 days prior to randomization
Serious non-healing wound ulcer, or bone fracture within 21 days prior to randomization
Persistent history of gross hemoptysis relating to the patient's NSCLC
Known HIV infection
Known to be positive for hepatitis C or hepatitis B surface antigen
Chronic daily treatment with aspirin or nonsteroidal anti-inflammatory agents known to inhibit platelet function
Use of anticoagulation therapy
Participation in clinical trials or undergoing other investigational procedures within 30 days prior to randomization
Pregnancy (e.g., positive HCG test) or breast feeding
Known sensitivity to any of the products to be administered during the study
Any disorder that compromises the ability of the patient to provide written informed consent and/or to comply with study procedures
