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COMPLETEDNCT00474773

Evaluation of Post Hospital Administration of Celecoxib Following Minimally Invasive Knee Replacement Surgery

This study will evaluate the benefits of continuing celecoxib through six weeks of total knee arthroplasty recovery. This is a randomized, double blind study with a group of approximately 130 primary ...

Lead sponsor: St. Louis Joint Replacement Institute•1 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

St. Louis Joint Replacement Institute

Collaborators

Pfizer
Zimmer Biomet

Age

All ages

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•having undergone a minimally invasive total knee by select surgeon
•voluntarily enrolled
•independent community ambulators
•only patients being discharged directly home

Exclusion Criteria

•celecoxib allergy or intolerence
•Renal insufficiency (defined as serum creatine level \>1.5 mg/dL or BUN level \>22mg/dL
•History of bleeding gastic or duodenal ulceration
•New York Heart Association Class III or IV Congestive Heart Failure
•Previous myocardial infarction or cerebralvascular event
•Severe inflammatory bowel disease
•Known coagulation abnormality or hepatic disease
•Chronic coumadin administration
•Refusal by primary or cardiac physician

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: April 28, 2016Terms

Trial snapshot

StatusCOMPLETED

Phase—

Enrollment107

Start dateJun 2007

Last updatedApr 28, 2016

Condition

Pain Management Function Minimally Invasive Total Knee Arthroplasty Celecoxib

Locations shown

DePaul Health Center

St Louis, Missouri

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: April 28, 2016Data synced to Clareo: July 13, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions