Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Genentech, Inc.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Histologically confirmed solid tumor that is metastatic or unresectable, and for which standard curative or palliative measures do not exist or are no longer effective, and there are no known therapies to prolong survival
Disease that is measurable according to Response Evaluation Criteria in Solid Tumors (RECIST)
Adequate organ and marrow function
Sexually active participants must use medically acceptable methods of contraception during the course of the study and at least 11 days after the last dose of study treatment
Female participants of childbearing potential must have a negative serum pregnancy test at screening
No other history of/or ongoing malignancy that would potentially interfere with the interpretation of the pharmacodynamic or efficacy assays
You may not be if
Anticancer treatment (e.g., chemotherapy, radiotherapy, cytokines, or hormones) within 28 days (6 weeks for nitrosoureas or mitomycin C, or 14 days for hormonal therapy or kinase inhibitors) before the first dose of study drug
The participant has not recovered to Grade \</=1 from adverse events (AEs) or to within 10% of baseline values due to investigational or other agents administered more than 28 days prior to study enrollment
The participant has received another investigational agent within 28 days of the first dose of study drug
Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, diabetes, symptomatic congestive heart failure, unstable angina pectoris, or cardiac arrhythmia
The participant is pregnant or breastfeeding
The participant is known to be positive for the human immunodeficiency virus (HIV)
Allergy or hypersensitivity to components of the cobimetinib formulation
Clareo Health | Study of Cobimetinib in Participants With Solid Tumors
