Naltrexone in the Treatment of Pyromania

Exclusion Criteria

• •1. unstable medical illness or clinically significant abnormalities on prestudy laboratory tests or physical examination;
• •2. history of seizures;
• •3. myocardial infarction within 6 months;
• •4. current pregnancy or lactation, or inadequate contraception in women of childbearing potential;
• •5. clinically significant suicidality;
• •6. current or recent (past 3 months) DSM-IV substance abuse or dependence;
• •7. illegal substance within 2 weeks of study initiation;
• •8. initiation of psychotherapy or behavior therapy from a mental health professional within 3 months prior to study baseline;
• •9. initiation of a psychotropic medication within 2 months prior to study inclusion;
• •10. previous treatment with naltrexone; and
• •11. treatment with investigational medication or depot neuroleptics within 3 months, with fluoxetine within 6 weeks, or with other psychotropics within 2 weeks prior to study baseline