Patients non susceptible for chemotherapy treatment
Measurable disease according to RECIST criteria
Age \> 18 years.
ECOG performance status \< 2.
Adequate bone marrow, hepatic, renal and respiratory function.
Patients capable of following an adequate therapeutic compliance and accessible for a correct follow-up.
Women at a fertile age must have a negative serum or urine pregnancy test within the 7 days prior to the beginning of the treatment.
Patients of both genders at a fertile age, including those women having their last menstruation within the two previous years, must follow effective contraceptive measures.
You may not be if
Prior chemotherapy or radiotherapy.
History of other curatively treated malignancy and no evidence of disease within the past 5 years except squamous cell skin cancer, or resected cervix carcinoma.
Pregnant or lactating women.
Any other severe disease or clinical conditions, as, but not only:
1. Unstable cardiopathy despite treatment, myocardial infarction within the 6 months before entering the study
2. Uncontrolled active infection
3. Uncontrolled peptic ulcer, unstable diabetes mellitus or any other contraindication for treatment with corticosteroids.
4. Autoimmune diseases.
Concomitant treatment with any other antineoplastic therapy.
Prior experimental pharmacological agent within the 3 weeks prior to the inclusion of the study.
Prior treatment with EGFR targeted therapies.
Erlotinib known hypersensibility.
Any radiotherapy treatment contraindication.
History of significant neurological or psychiatric disorders, including epileptic seizures.
Any significant ophthalmologic impairment of the eye surface (Use of contact lenses is not recommended)
Inability to take oral medication and surgical procedures affecting the absorption or implying intravenous or parenteral feeding.
Any other underlying severe process affecting the ability to take part in the study.
Clareo Health | Study of 3D Radiotherapy With or Without Erlotinib (Tarceva®) in Patients With Localized Non-Small Cell Lung Cancer
