Medical History

Serious local infection or systemic infection within 3 months of Day 0

History (Hx) of recurrent infections requiring oral or parental anti-infective treatment

Hx of tuberculosis (TB) or positive purified protein derivative (PPD) test during the screening period

Laboratory Tests

Clinically significant lab tests at screening; or

Positive for hepatitis C antibody or hepatitis B at screening

BG9924 in Combination With Methotrexate for Participants With Active Rheumatoid Arthritis