Asimadoline for the Treatment of Subjects With Irritable Bowel Syndrome

Inclusion Criteria

• •Males and females aged 18-79
• •Must sign an ICF
• •Females of childbearing potential must have a negative pregnancy test at screening and must adhere to contraception throughout the trial
• •Must have been diagnosed with IBS as a result of having at least 6 months, not necessarily consecutive, in the preceding 12 months of recurrent symptoms of abdominal discomfort or pain associated with at least 2 of the following: 1)relieved with defecation; 2)onset associated with a change in stool frequency; 3)onset associated with a change in stool form
• •Must demonstrate a willingness to comply with daily telephone diary entry