Finding studies
Finding studies
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Saves the questions and what to expect into your notes, next to the visit they belong to.
Lead
Dana-Farber Cancer Institute
With
OBJECTIVES: Primary * To determine the response rate of patients with metastatic mucosal, acral/lentiginous, or chronically sun damaged melanomas to treatment with of imatinib. * To determine the time to progression. Secondary * To correlate c-kit mutational status with response to therapy. * To evaluate the use of FDG-PET scanning in determining early biologic response to therapy. * Tolerability of imatinib. * To assess amplification of c-kit status through quantitative PCR and/or FISH and other related molecular pathway targets. * To correlate c-kit amplification status with response to therapy.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted