Dietary Advanced Glycation End-products and Insulin Resistance in Overweight and Obese Humans

Exclusion Criteria

• •Participants will be excluded if they:
• •* are aged \<18 years or \> 50 years;
• •* currently smoke, have high alcohol use; or a positive urine drug screening test;
• •* have a history of: diabetes, cardiovascular and hematological disease, respiratory, gastrointestinal, endocrine, renal or central nervous system disease, psychosis or psychiatric disorder, active cancer within last 5 years.
• •* are actively seeking to lose weight, or if their weight has changed by more than 10 kilograms in the previous 12 months.
• •* have been taking medication within one month prior to commencing the study;
• •* have acute inflammation (by history, physical or laboratory examination)
• •* are on hormonal contraceptives, or pregnant (by HCG urine pregnancy screening test) or lactating
• •* have highly unusual dietary habits or follow vegan diets (because of the difficulty in complying with the assigned diet).
• •* have current diabetes (determined by history and/or 75g glucose OGTT)
• •* are unable to provide informed consent