Patients not meeting above stated age criteria

Females that are pregnant or lactating (non pregnant females of childbearing potential will have pregnancy test prior to participating in study)

History of serious ocular, neurological, cardiovascular disease

History of severe systemic disease

History of arrhythmias or high blood pressure

Patients currently taking any type of ocular or systemic medications except multivitamins.

Patients with abnormal pupil shape, Addie's pupil, anisocoria, or abnormal pupil defect.

Effect of Brimonidine Tartrate Ophthalmic Solution 0.15% on Pupil Diameter in Normal Eyes