ProQuad® Intramuscular vs Subcutaneous

Exclusion Criteria

• •Prior receipt of measles, mumps, rubella and/or varicella vaccine either alone or in any combination,
• •Any recent (≤30 days) exposure to measles, mumps, rubella, varicella and/or zoster
• •Any recent (≤3 days) history of febrile illness
• •Any severe chronic disease,
• •Active untreated tuberculosis,
• •Known personal history of seizure disorder,
• •Any known blood dyscrasias, leukemia, lymphomas of any type, or other malignant neoplasms affecting the haematopoietic and lymphatic systems,
• •Any severe thrombocytopenia or any other coagulation disorder that would contraindicate intramuscular injection,
• •Any immune impairment or humoral/cellular deficiency, neoplastic disease or depressed immunity including those resulting from corticosteroid \[any long-term (≥14 days) administration of systemic corticosteroid therapy given daily or on alternate days at high doses (≥2 mg/kg/day prednisone equivalent or ≥20 mg/day if weight more than 10 kg) within the previous 30 days\] or other immunosuppressive therapy,
• •Any previous (≤ 150 days) receipt of immune globulin or any blood-derived product or scheduled to be administered through Visit 3,
• •Any recent (≤7 days) tuberculin test or scheduled tuberculin test through Visit 3,
• •Any recent (≤30 days) receipt of an inactivated or a live vaccine or scheduled vaccination through Visit 3,