Is allergic to or has a serious reaction to hydrocodone, acetaminophen, lidocaine, propofol, morphine sulfate, oxycodone, and/or similar drugs

Is allergic to or has a serious reaction to aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs)

Has a history of certain gastrointestinal diseases that may narrow or slow down the gastrointestinal tract

Has specific active or uncontrolled seizure disorders

Has been diagnosed with certain cancers within the past 5 years

Has a history of certain psychiatric disorders or requires treatment with certain drugs for depression

Has specific clinically significant illnesses or laboratory abnormalities

Has received corticosteroid treatment or any investigational drug within a specific timeframe

A Study of Extended-Release Hydrocodone/Acetaminophen (Vicodin CR®) in Subjects With Acute Pain Following Bunionectomy