Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Mallinckrodt
The research hypothesis is that IV Acetaminophen will provide greater reduction in pain intensity and greater pain relief for moderate and severe pain as compared to placebo in the 48 hours following surgery.
Age
18–75
Sex
FEMALE
Healthy volunteers
Not accepted
You may be eligible if
Undergo gynecologic surgery using standard abdominal approach such as midline or Pfannenstiel incision
18-75 years of age
Body Mass Index (BMI) between 19-45
American Society of Anesthesiologists (ASA) risk class of I, II, III
Not have received neuraxial (spinal or epidural) opioid analgesics prior to or during surgery
Moderate to Severe pain at rest
You may not be if
Requires any additional surgical procedures either related or unrelated to gynecologic surgery during same hospitalization
Procedures involving only minimal incisions such as laparotomy, laparoscopy, supraumbilical or Maylard incisions
Has know hypersensitivity to opioids, acetaminophen, or the excipients of IV acetaminophen
Known history of alcohol or drug abuse or misuse
Has impaired liver function Aspartate transaminase(AST), Alanine aminotransferase(ALT), bilirubin greater than or equal to 2 times upper limit of normal
Has significant medical disease(s), or conditions that may contraindicate participation in the study
Has participated in another clinical trial within 30 days of surgery
Clareo Health | Efficacy and Safety of Intravenous Acetaminophen Over 48 Hrs for the Treatment of Post-op Pain After Gynecologic Surgery
