Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Forest Laboratories
Escitalopram is the S-enantiomer of citalopram. Both escitalopram and citalopram are selective serotonin reuptake inhibitors (SSRIs) and are used to treat depression in adults. This study is designed to evaluate the safety and efficacy of escitalopram and an active comparator in severely depressed patients.
Age
18–65
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Patients must meet DSM-IV criteria for Major Depressive Disorder.
Patients must have severe depression.
MADRS greater than or equal to 30
You may not be if
Women who are pregnant, women who will be breastfeeding during the study, and women of childbearing potential who are not practicing a reliable method of birth control.
Patients who are considered a suicide risk.
Patients who currently meet DSM-IV criteria for: a principal diagnosis for Axis I disorder other than MDD (comorbid GAD is allowed), bipolar disorder, schizophrenia or any psychotic disorder, obsessive-compulsive disorder, dysthymia.
Patients with a family history of bipolar disorder, schizophrenia, or any psychotic disorder.
Patients with history of any psychotic disorder or any psychotic feature.
