Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Danish Headache Center
To investigate headache score and accompanying symptoms during and after infusion of PACAP38
Changes in regional cerebral blood flow (rCBF) in the area supplied by middle cerebral artery (MCA), blood flow in MCA, diameter of the superficial temporal artery (STA) and radial artery (RA)
Age
18–50
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Healthy migraine patient without aura
Aged 18-50
50-100 kg
Fertile women must use safe contraceptives (IUD, oral contraceptives, surgical sterilisation and long lasting gestagen.
You may not be if
Tension type headache more than five times/month
Other primary headaches
Daily medication except contraceptives
Drug taken within 4 times the halflife for the specific drug except contraceptives
Pregnant or lactating women
Exposure to radiation within the last year
Headache within the last 48 hours before start of trial
Hypertension
Hypotension
Respiratory or cardiac disease
Clareo Health | PACAP38´s (Pituitary Adenylate Cyclase-Activating Polypeptide) Headache Inducing Characteristics and Effects on the Cerebral Blood Flow
