Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Women who suffer with urge incontinence may not get relief with usual medical treatment (such as medications or behavioral techniques). We plan to enroll women with refractory urge incontinence in centers across the US. Study participants will undergo cystoscopy (telescope look into the bladder) and injection of either Botox A or placebo. If symptoms are not adequately relieved, subjects participants will receive a second injection that is Botox A. Participants are interviewed monthly by study personnel to determine symptoms and health status.
Age
21–any
Sex
FEMALE
Healthy volunteers
Not accepted
You may be eligible if
Adult women
Detrusor overactivity incontinence confirmed by urodynamic testing
Symptoms refractory to standard first- and second-line treatments
6 or more urge incontinence episodes on 3-day bladder diary
Normal neurological examination
You may not be if
Urinary retention
Allergy to Botox (Botulinum Toxin A)
Previous bladder treatment with Botox (Botulinum Toxin A) in the past year
Pregnancy or planning pregnancy within next year
Neurologic disease with impaired neurotransmission
