Comparing the Efficacy of Tacrolimus and Mycophenolate Mofetil for the Initial Therapy of Active Lupus Nephritis

Exclusion Criteria

• •1. Patients who refuse to be randomized for treatment
• •2. Patients who prefer treatment with conventional agents such as oral or intravenous CYC for various reasons
• •3. Serum creatinine \>= 200 umol/L at the time of randomization
• •4. Patients without renal biopsy or those who have lupus nephritis ISN/RPS class I,II,VI
• •5. Patients who are pregnant or plan for pregnancy within 12 months after randomization