Patients who have taken any NNRTI prior to their current therapy.

Patients who have taken a NRTI-only therapy for greater than 7 days prior to their current therapy.

Patients who are currently taking EFV+FTC+TDF.

Patients who have a creatinine clearance of \<60 mL/min by Cockcroft-Gault estimation.

Patients who have experienced virologic failure with any previous ARV therapy.

Patients who have documented resistance to any of the study agents at any time in the past.

Single Tablet Regimen (STR) Simplification Study for HIV-1 Infected Patients