Prevention of Radiation Pneumonitis After Three-dimensional Conformal Radiation Therapy (3D-CRT) in Patients With Non-small-cell Lung Cancer

Inclusion Criteria

• •Non-metastatic cytologically or histologically proven non-small-cell lung cancer (NSCLC)
• •Operated NSCLC patients requiring post-surgical irradiation or non-operated NSCLC patients requiring curative irradiation
• •Conformational thoracic radiotherapy with curative intent
• •Age \>= 18
• •Complete functional respiratory evaluation (FRE) performed less than 2 months before inclusion, demonstrating a maximum expiratory flow-volume/second \> 1 l (in case surgery, the FRE must have been realized in the post-surgery period)
• •Thoracic CT-scan performed less than 2 months before inclusion for non-operated patient
• •PET-scan performed less than 2 months before inclusion for non-operated patient
• •Performance status (PS) ECOG \<= 1
• •Possible training on breath holding technique
• •Female patients of childbearing potential: effective method of contraception necessary
• •Mandatory affiliation with a social security system
• •Written, signed, informed consent