Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Canadian Immunodeficiency Research Collaborative
With
National Institutes of Health (NIH)
Primary HIV-1 infected and chronically infected individuals will be recruited and leukapheresis will be performed. This one year study requires that patients be apheresed once before initiating therapy and on two other occasions (at month 6 and month 12) after suppression of plasma viremia. Peripheral blood mononuclear cells will be isolated by sodium diatrizoate density centrifugation and subjected to immunologic and virologic studies.
Age
18–50
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Adult HIV-1 infected patient
For primary infected patients anyone with an exposure to a known source of HIV infected material or individual, with symptoms and signs if present consistent with primary HIV infection, a negative ELISA, indeterminate Western blot for HIV and a positive HIV plasma RNA levels \> 10,000 copies/mL by either RT-PCR or bDNA
Chronic HIV-infected patients should have a positive ELISA and a confirmatory western blot and willingness to give informed consent for the storage of blood.
Willingness to be able to make follow-up visits for apheresis at 6 and 12 months for those who undergo antiretroviral therapy
You may not be if
Pregnant women
Clareo Health | Leukapheresis to Obtain Lymphocytes for Studies on Antiretroviral Naive HIV-infected Patients
