Adult subjects ≥ 50 years of age.

minimally classic or active occult choroidal neovascularization associated with age-related macular degeneration in one or both eyes.

baseline best corrected visual acuity score between 35 to 65 letters according to the Early Treatment of Diabetic Retinopathy Study protocol.

central retinal thickness by optical coherence tomography of \> 250 microns.

lesions \> 9 disc areas.

\> 25% fibrosis in the lesion.

A Study of MSI-1256F (Squalamine Lactate) To Treat "Wet" Age-Related Macular Degeneration