Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Syntara
This study will assess and compare the safety and tolerability of inhaled TPI 1020 versus budesonide. Pharmacokinetic (PK) and pharmacodynamic (PD) parameters will also be studied in a sub-group of subjects.
Age
18–65
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Males or females 18 through 65 years of age.
Smoking history of more than 5 pack/years but less than 25 pack/years and who have no desire to quit smoking despite physician's advice and who currently smoke at least 5 cigarettes per day.
Mild to moderate, stable, allergic asthma as defined by American Thoracic Society (ATS) criteria 1
History of episodic wheeze and shortness of breath
Subjects currently and only receiving inhaled short-acting bronchodilator treatment for asthma.
You may not be if
History or symptoms of significant autoimmune, hematological, or neurological disease, including transient ischemic attack (TIA), stroke, seizure disorder, or behavioural disturbances that are judged clinically significant by the Investigator
History of serious adverse reaction or hypersensitivity to corticosteroids
Abnormal chest X-ray that is judged clinically significant
Pregnant or lactating or have positive plasma pregnancy test
Use of oral/parenteral/inhaled corticosteroids within the last 28 days or injectable depot corticosteroids within the last 6 weeks.
Use of any other asthma-related medications within 1 month of Screening
