Finding studies
Finding studies
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Lead
University Hospitals Cleveland Medical Center
With
* Single-center, open label study of pioglitazone in clinically stable patients with mild to moderate CF lung disease * Induced sputum will be obtained from each subject at enrollment (Baseline) and again following 28 days of pioglitazone treatment (End of Treatment) * Changes in markers of inflammation in the sputum samples will be assessed * Safety measures, including complete blood count (CBC), serum chemistry, Erythrocyte sedimentation rate (ESR), C-Reactive Protein (CRP), urinalysis and spirometry, will also be assessed
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted