Double-blind, Randomized, Placebo-controlled Phase 3 Study of Etanercept in the Treatment of Psoriatic Arthritis and Psoriasis

Previously presented data from 2 double-blind, placebo-controlled trials (Protocols 016.0612 \[Investigator IND\] and 016.0030 \[Immunex IND\]) led to the approval of etanercept for reducing clinical signs and symptoms of PsA. One-year radiographic data from Protocol 20021630 led to an additional approval of etanercept for inhibiting structural progression in PsA. Data are used for the following purposes: * To summarize the clinical efficacy and safety results previously described in the 6-month clinical study report and the radiographic results previously described in the 1-year clinical study report. * To show the effect of etanercept on physical function in subjects with PsA and psoriasis, as measured by 2 patient-reported outcome measures (disability index of the Stanford Health Assessment Questionnaire \[HAQ\] and Medical Outcomes Study Short-form Health Survey \[SF-36\]). • To present the radiographic results at 2 years from baseline and the final clinical efficacy and safety results during the open-label period of the study.