Finding studies
Finding studies
Take this into the appointment.
Saves the questions and what to expect into your notes, next to the visit they belong to.
Lead
SRI International
With
OBJECTIVES: * Determine the effectiveness of varenicline with telephone counseling vs Internet-based counseling vs telephone counseling and Internet-based smoking cessation interventions in adult smokers. * Determine individual or group differences in patients undergoing these interventions. * Determine heterogeneity in responsiveness in regard to the Classification and Regression Tree Analysis in patients undergoing these interventions. * Determine the effectiveness of these interventions in regard to recruitment, implementation, barriers to treatment, exposure to intervention, satisfaction with treatment, treatment contamination, and program maintenance. * Determine the cost-effectiveness of these interventions. OUTLINE: This is a randomized, open-label study. Patients are randomized to 1 of 3 intervention arms. * Arm I: Patients undergo a proactive telephone-based (PTB) smoking cessation program. * Arm II: Patients undergo a web-based (WB) smoking cessation program. * Arm III: Patients undergo an integrated PTB/WB smoking cessation program. Beginning 1 week before the target quit date, all patients receive oral varenicline once daily for 3 days and then twice daily for up to 12 weeks. They also receive a mailed packet containing a welcome letter, description of the intervention services offered, a privacy notice, a Free \& Clear Quit Kit (comprehensive education/self-help materials including health smoking substitutions), a phone call to orient the patient to the intervention to which they are randomized, and access to a toll-free support line. All patients undergo a pre-treatment assessment (pre-quit) and 3 post-quit assessments at 21 days, 12 weeks, and 6 months after their original scheduled quit date to determine medication adherence, treatment utilization, point-prevalent smoking outcomes, and continuous nonsmoking. PROJECTED ACCRUAL: A total of 1,200 patients will be accrued for this study.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
