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PGI2 Induced Headache and Cerebral Haemodynamics in Healthy Volunteers | Clinical Trials | Clareo Health

TERMINATEDPHASE1

PGI2 Induced Headache and Cerebral Haemodynamics in Healthy Volunteers

NCT00291395•Danish Headache Center

Summary

Before , during and after intravenous administration of PGI2 we score/measure headache, rCBF, blood flow in middle cerebral artery and diameter of superficial temporal artery/radial artery and correlate that to known patophysiology of headache to see if PGI2 is involved in headache pathophysiology.

Eligibility

Age

18 - 40 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Healthy volunteers,

Exclusion Criteria

•Primary headache,
•headache on the day of investigation,
•Hypertension,
•hypotension,
•pregnant/nursing
•Daily intake of medication (except oral contraceptives)
•Cardiovascular or CNS disease
•Drug/Alcohol abuse
•Psychiatric disease

Locations (1)

Danish Headache Center

Glostrup Municipality, Glostrup, Denmark

Key Dates

Start Date

September 1, 2005

Last Updated

October 26, 2006

Enrollment

Estimated participants

Conditions

HeadacheMigraine

Interventions

PGI2

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: October 26, 2006Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

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PGI2 Induced Headache and Cerebral Haemodynamics in Healthy Volunteers

Inclusion Criteria

Exclusion Criteria

A Study to Learn About the Study Medicine Called Rimegepant in Women When Used for Intermittent Prevention of Menstrual Migraine

A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Chronic Migraine

Mind Body Balance for Pediatric Migraine

Light Exposure, Migraine Outcomes, and Sleep Quality

MyVitalC: Sleep and Everyday Headache Management

A Study to Learn About the Study Medicine Called Rimegepant in Adolescents With Frequent Migraine