Finding studies
Finding studies
Take this into the appointment.
Saves the questions and what to expect into your notes, next to the visit they belong to.
Lead
Masonic Cancer Center, University of Minnesota
OBJECTIVES: Primary * Determine the maximum tolerated dose of metronomic docetaxel in patients with progressive or recurrent gynecologic cancer. Secondary * Determine the response rate in patients treated with this drug. * Determine the pharmacokinetics associated with this drug in these patients. OUTLINE: This is a dose-escalation study. Patients receive docetaxel intravenously (IV) over 1-2 minutes daily for up to 6 months in the absence of unacceptable toxicity. Cohorts of 3-6 patients receive escalating doses of docetaxel until the maximum tolerated dose (MTD) is determined. The MTD is defined as the dose preceding that at which 2 of 3 or 2 of 6 patients experience dose-limiting toxicity. After completion of study treatment, patients are followed every 3 months.
Age
18–any
Sex
FEMALE
Healthy volunteers
Not accepted