Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Symphony Evolution, Inc.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Males and females with histologically confirmed NSCLC
Prior treatment with a platinum- or taxane containing regimen
Stage IIIB with malignant effusion, stage IV or recurrent NSCLC that is not amenable to curative therapy (either surgery or radiation therapy)
Measurable disease according to Response Criteria for Solid Tumors (RECIST)
ECOG performance status of 0 or 1
Life expectancy ≥3 months
Adequate organ and marrow function
No other malignancies within 5 years
Signed informed consent
You may not be if
Radiation to ≥25% of bone marrow within 30 days of XL999 treatment
Use of any systemic anticancer therapy within 30 days of XL999 treatment
More than 2 prior systemic cytotoxic chemotherapy regimens
More than 1 prior agent targeted against VEGF or EGFR (eg, bevacizumab, erlotinib, or gefitinib)
Subject has not recovered to ≤ grade 1 or to within 10% of baseline from adverse events due to other medications administered \>30 days before study enrollment
Uncontrolled and/or intercurrent illness
History of or known brain metastases, current spinal cord compression, or carcinomatous meningitis
Pregnant or breastfeeding females
Known HIV
Clareo Health | Study of XL999 in Patients With Non-small Cell Lung Cancer