Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
GlaxoSmithKline
Age
18–65
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Healthy subjects suffering from moderate to severe migraine headache with or without aura.
Women of child bearing potential must use an effective method of contraception.
Have had at least a 1 year history of migraine and the age of onset was prior to 50 years.
Suffering 1 to 6 migraine attacks per month for at least the last 3 months and should have at least 48 hours free of headache between migraine attacks.
You may not be if
Headache for 15 days/month or greater in any of the three months (90 days) preceding entry into the study.
Use of migraine medications (e.g., ergotamine, triptan, opioid, or combination medication) on \>/= 10 days per month on a regular basis for \>/= 3 months.
Use of analgesics \>/=15 days per month for \>/=3 months, uses an opiate (except codeine) as first line treatment for migraine.
Migraine symptoms do not respond to any of the triptan drugs (e.g., Imitrex, Relpax, Maxalt).
Have uncontrolled hypertension or a history/ presence of multiple cardiovascular risk factors such as, but not limited to family history, myocardial infarction, coronary artery disease, vasospastic angina, heart failure, cardiac arrhythmias or history or presence of cerebrovascular disease, including transient ischemic attack, stroke or peripheral arterial disease.
History of alcohol, substance or drug abuse within the last year.
Participation in a trial with a new chemical entity within 3 months before the start of the study.
Participation in any other research trial within 30 days prior to the first dose of current study medication is not permitted.
