Expanded Access Study Of BEXXAR® For Low Grade And Transformed Low-Grade Non-Hodgkin's Lymphoma

Exclusion Criteria

• •Patients with a mean of \>25% of the intratrabecular marrow space involved with lymphoma.
• •Patients who received cytotoxic chemotherapy, radiation therapy, immunotherapy, or cytokine treatment within 4 weeks prior to study entry (6 weeks for nitrosurea compounds) or who exhibit persistent clinical evidence of toxicity.
• •Patients who have undergone stem cell or bone marrow transplant, active obstructive hydronephrosis, active infection, New York Heart Association Class III or IV heart disease or other serious illness that would preclude evaluation.
• •Known HIV infection.
• •Pregnant or nursing patients.
• •Patients with prior malignancy other than lymphoma, except for adequately-treated skin cancer, in-situ cervical cancer, or cancer for which the patient has been disease-free for 5 years.
• •Patients with progressive disease within 1 year of irradiation arising in a field that has been previously irradiated with more than 3500 cGy.
• •Patients who received prior radioimmunotherapy, known brain or leptomeningeal metastases, HAMA positivity.
• •Patients who are receiving either approved or non-approved (through another protocol) anti-cancer drugs or biologics.