Patients with previous malignancies other than NSCLC

Previous radiotherapy for NSCLC

Previous immunotherapy or chemotherapy

Any unresolved chronic toxicity greater than CTC grade 2 from previous anticancer therapy

Forced expiratory volume in 1 second (FEV1) less than 1 litre (L)

Absolute neutrophil count (ANC) less than 1.5 x 109/L or platelets less than 100 x 109/L

Serum bilirubin greater than 1.25 times the upper limit of reference range

ALT or AST greater than 2.5 times the ULRR

ZD1839 (Iressa™) and Concurrent Chemo-Radiation in Patients With Locally Advanced Non Small Cell Lung Cancer