Efficacy and Safety (Including 24-hour Holter Monitoring) of Tiotropium Inhalation Capsules in Patients With COPD

You may be eligible if

• History of COPD, FEV1 less than or equal to 65%, FEV1/FVC less than or equal 70%
• Smoking history greater than or equal to 10 pack years
• Not history of clinical diagnosis of asthma and/or atopy
• A history of thoracotomy with pulmonary resection
• Patients requiring the use of supplemental oxygen therapy for \>12 hours per day
• Chronic use of systemic corticosteroids in an unstable daily dose
• Patients with a recent history of myocardial infarction
• A known hypersensitivity to anticholinergic drugs