Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Melbourne Health
With
Boehringer Ingelheim
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Patients who present:
with acute hemispheric stroke within 3-6 hours of onset,
have at least moderate limb weakness,
a National Institute of Health Stroke Scale (NIHSS) score \> 4,
had a pre-stroke modified Rankin Scale (MRS) score of 0 - 2
and who are able to undergo CT and MRI, are eligible for this study.
You may not be if
Females who are pregnant or breast-feeding,
persons who have CT-verified hemorrhagic stroke, major ischemia ( \> 33% of the middle cerebral artery (MCA) territory infarcted), subarachnoid hemorrhage, arteriovenous malformation, aneurysm, intracranial neoplasm that is terminal or poses a risk of hemorrhage ,
are comatose or severely obtunded with fixed eye deviation and complete hemiplegia,
have had another stroke within the past 6 weeks,
have had a seizure prior to the administration of the study drug,
have active peptic ulceration, bleeding diatheses, previous intracerebral hemorrhage,
blood pressure \> 185/110,
major surgery or trauma within the past 30 days, or any other contraindications to tPA
have a presumed septic embolus or a myocardial infarction within the past 30 days
blood glucose values are \< 2.8 or \> 22.0 mmol/L,
pacemakers, aneurysm clips, implanted devices, claustrophobia, or any other contraindications to MRI,
